Correlation between glycated hemoglobin level and hypertension in Libyans with type- II diabetes mellitus

Abstract

Objective: Hypertension and diabetes are closely related morbidities. There is research examining the correlation between blood pressure (BP) and glycated hemoglobin (HbA1c) levels in diabetes mellitus. The objective of the current study was to investigate the correlation between high BP and glycated hemoglobin (HbA1c) levels. Materials and methods: In a cross-sectional study, 47 diabetic patients in (Diabetes & Endocrinology Center Tripoli – Libya) were chosen. Blood pressure was measured using a mercury sphygmomanometer, and Serum HbA1c and Lipids were measured by enzymatic method Cobas Integra. HbA1c was measured by immunoturbidimetric ally COBAS INTEGRA. Correlation (Pearson) analysis was used to explore the association between hypertension and hyperglycemia. Independent risk factors for systolic and diastolic BP were analyzed using correlation. Results: Subjects in HbA1c group type-II diabetes mellitus (n = 47), as compared with healthy control HbA1c (n = 23). There were strong significant correlations between glycated hemoglobin (HbA1c) and Systolic blood pressure (SBP) (r=0.436**, P=0.001), significant correlations between glycated hemoglobin and Diastolic blood pressure (DBP) (r=0.133, P=0.269), had a significantly higher risk for hypertension, respectively. correlation analysis revealed that HbA1c was an independent factor of systolic and diastolic BP. Conclusions: The study presents a correlation between hyperglycemia and hypertension in type-II diabetes, our findings suggest that hyperglycemia as well as higher HbA1c within the type-II diabetes range is associated with a higher prevalence of hypertension independent of other cardiovascular risks.