International Blood Transfusion Regulations: Considerations, Safety Precautions Discussion, and Preliminary Testing Precedents Before Transfusion: Minireview

Authors

  • Amal Ismail Joudeh Department of Medical Laboratory Sciences at the Faculty of Medical Technology, Wad Alshatti University Author

DOI:

https://doi.org/10.54361/LJMR.19.2.11

Keywords:

Blood transfusions, Discussion, study, Preliminary Testing Precedents

Abstract

Blood transfusions form a network of integral medical processes for trauma, surgical interventions, and management of chronic diseases all over the world. Nonetheless, different infrastructures in different countries tailor recruitment of donors and policy execution, guaranteeing a safe, sufficient, and equitable blood supply, continue to be challenged. This study examined international blood transfusion policies: donor systems, clinical procedures, safety standards, and pre-transfusion testing guidelines, backed by such key health organizations as AABB and the World Health Organization. Important areas of concern include the incidence of transfusion-transmissible infections (TTIs), the encouragement of voluntary non-remunerated blood donation (VNRBD), the imposition of stringent transfusion practices, and the imposition of laboratory testing before transfusion. Evidence-based suggestions will be put forward towards improving global standards for blood safety and availability using data from PubMed and other reliable sources.

Downloads

Download data is not yet available.

References

1. Carson JL, Guyatt G, Heddle NM, et al. Red Blood Cell Transfusion: 2023 AABB International Guidelines. JAMA. 2023.

2. World Health Organization. Blood Safety and Availability. Geneva: WHO; 2025.

3. Alemu M, Tadesse A, Yihun B, et al. Evaluation of Transfusion Transmissible Infections Prevalence. PMC. 2022.

4. International Federation of Red Cross and Red Crescent Societies. Policy Promoting Safe and Sustainable National Blood Systems. Geneva: IFRC; 2011.

5. Jahr JS, Akha AS, Guinn NR. Ways to Enhance Blood Transfusion Safety: A Systematic Review. PMC. 2008.

6. World Health Organization. Blood Safety. Geneva: WHO; 2011.

7. Thalassaemia International Federation. Blood Safety & Availability. Nicosia: TIF; 2024.

8. Arora D, Kumar A, Sharma S. Prevalence of Transfusion Transmissible Infections Among Various Populations. PMC. 2025.

9. Napolitano LM, Kurek S, Luchette FA, et al. Indications for Blood and Blood Product Transfusion. PMC. 2014.

10. Lacroix J, Hébert PC, Hutchison JS, et al. Transfusion Strategies for Patients in Pediatric Intensive Care Units. N Engl J Med. 2007;356(16):1609-19.

11. Hébert PC, Wells G, Blajchman MA, et al. A Multicenter, Randomized, Controlled Clinical Trial of Transfusion Requirements in Critical Care. N Engl J Med. 1999;340(6):409-17.

12. Villanueva C, Colomo A, Bosch A, et al. Transfusion Strategies for Acute Upper Gastrointestinal Bleeding. N Engl J Med. 2013;368(1):11-21.

13. Hajjar LA, Vincent JL, Galas FR, et al. Transfusion Requirements After Cardiac Surgery: The TRACS Randomized Controlled Trial. JAMA. 2010;304(14):1559-67.

14. Salpeter SR, Buckley JS, Chatterjee S. Red Blood Cell Transfusion Policy: A Critical Literature Review. PMC. 2017.

15. Kim Y, Kim HJ, Park KU, et al. Evaluation of Pre-Transfusion Crossmatch Test Using Microscanner. PMC. 2024.

16. European Commission. Summary of the 2022 Annual Reporting of Serious Adverse Reactions and Events in Blood Transfusion. Brussels: EU Health Directorate; 2023.

17. Holcomb JB, Tilley BC, Baraniuk S, et al. Transfusion of Plasma, Platelets, and Red Blood Cells in a 1:1:1 vs a 1:1:2 Ratio and Mortality in Patients With Severe Trauma. JAMA. 2015;313(5):471-82.

18. World Health Organization. Clinical transfusion process and patient safety. WHO/EHT/10.05.

Downloads

Published

01-07-2025

Issue

Section

Articles

How to Cite

1.
Joudeh A. International Blood Transfusion Regulations: Considerations, Safety Precautions Discussion, and Preliminary Testing Precedents Before Transfusion: Minireview . LJMR [Internet]. 2025 Jul. 1 [cited 2025 Jul. 16];19(2):92-8. Available from: https://ljmr.ly/index.php/ljmr/article/view/389

Similar Articles

11-20 of 197

You may also start an advanced similarity search for this article.