Evaluation of medical equipment of the infertility treatment centers in North western of Libya
DOI:
https://doi.org/10.54361/LJM17-2.15Keywords:
ICSI, IVF, Instruments, Equipment, laboratory,, , Infertility, LibyaAbstract
Background Cell culture, particularly in vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI) are both of which assisted reproductive technology (ART) approaches that are most frequently utilized to treat infertility around the world. Objective Highlight the differences and similarities in instruments and equipment in ART laboratories that govern their success, limitations, and potential differences between laboratories by identifying the facilities of laboratories to improve outcomes of ICSI and IVF techniques in clinical centers on the western coast of Libya. Method: descriptive study, comparison of five (5) assisted reproduction laboratories instrument and equipment parameters using the same quality-control application in clinical centers on the western coast of Libya.Result: Among the seven clinical centers specializing in the diagnosis and treatment of infertility that were contacted, four infertility treatment centers and the Medical Research Center (MRC) provided a response. The MRC and four clinical centres had good laboratory facilities for ICSI and IVF techniques compared to Jordan ART laboratory facilities.Conclusion: This study highlights the imperative of enhancing laboratory infrastructure to support optimal implementation of ICSI and IVF procedures.
References
Wirka KA, Maldonado Rosas I, Anagnostopoulou C, Singh N, Manoharan M, Barros B, Leonardi Diaz SI, Gugnani N, Desai D, Boitrelle F, Sallam HN, Agarwal A. Taking a closer look at the key performance indicators in an assisted reproductive technology laboratory: a guide for reproductive professionals. Panminerva Med. 2022 Jun;64(2):200-207. doi: 10.23736/S0031-0808.22.04686-9. Epub 2022 Feb 18. PMID: 35179018. DOI: https://doi.org/10.23736/S0031-0808.22.04686-9
Jain M, Singh M. Assisted reproductive technology (ART) techniques. InStatPearls [Internet] 2022 Nov 28. StatPearls Publishing.
Aggarwal B, Evans AL, Ryan H, Martins da Silva SJ. IVF or ICSI for fertility preservation? Reproduction and Fertility. 2021; 2(1): L1-L3. DOI: https://doi.org/10.1530/RAF-20-0059
Sallam H, Boitrelle F, Palini S, Durairajanayagam D, Parmegiani L, Jindal S, Agarwal A. ICSI for non-male factor infertility: time to reappraise IVF? Panminerva Med. 2023; 65(2): 159-165. DOI: https://doi.org/10.23736/S0031-0808.23.04869-3
Bormann CL. Assisted Reproductive Technology: Laboratory Aspects. In: Falcone T, Hurd W, editors. Clinical Reproductive Medicine and Surgery. Cham: Springer; 2017. p. 271-287. DOI: https://doi.org/10.1007/978-3-319-52210-4_18
Amigh KS. Fertilization: Conventional IVF Versus ICSI. In: Bukulmez O, editor. Diminished Ovarian Reserve and Assisted Reproductive Technologies. Cham: Springer; 2020. p. 261-270. DOI: https://doi.org/10.1007/978-3-030-23235-1_18
Boulet SL, Mehta A, Kissin DM, Warner L, Kawwass JF, Jamieson DJ. Trends in use of and reproductive outcomes associated with intracytoplasmic sperm injection. Jama. 2015 Jan 20;313(3):255-63. DOI: https://doi.org/10.1001/jama.2014.17985
Palmer GA, Kratka C, Szvetecz S, Fiser G, Fiser S, Sanders C, Tomkin G, Szvetecz MA, Cohen J. Comparison of 36 assisted reproduction laboratories monitoring environmental conditions and instrument parameters using the same quality-control application. Reproductive BioMedicine Online. 2019 Jul 1;39(1):63-74.
ESHRE Guideline Group on Good Practice in IVF Labs, De los Santos MJ, Apter S, Coticchio G, Debrock S, Lundin K, Plancha CE, Prados F, Rienzi L, Verheyen G, Woodward B. Revised guidelines for good practice in IVF laboratories (2015). Geneva: European Society of Human Reproduction and Embryology; 2015.
International Organization for Standardization. General requirements for the competence of testing and calibration laboratories. ISO 17025:2017. Geneva, Switzerland: International Organization for Standardization; 2017.
International Organization for Standardization. Quality management systems — Requirements. ISO 9001:2015. Geneva, Switzerland: International Organization for Standardization; 2015.
International Organization for Standardization. Medical laboratories — Requirements for quality and competence. ISO 15189:2012. Geneva, Switzerland: International Organization for Standardization; 2012.
International Organization for Standardization. Biotechnology — Biobanking — General requirements for biobanking. ISO 20387:2018. Geneva, Switzerland: International Organization for Standardization; 2018.
International Organization for Standardization. Biological evaluation of medical devices — Part 1: Evaluation and testing within a risk management process. ISO 10993-1:2018. Geneva, Switzerland: International Organization for Standardization; 2018.
International Organization for Standardization. Medical devices — Quality management systems — Requirements for regulatory purposes. ISO 13485:2016. Geneva, Switzerland: International Organization for Standardization; 2016.
Palmer GA, Kratka C, Szvetecz S, Fiser G, Fiser S, Sanders C, Tomkin G, Szvetecz MA, Cohen J. Comparison of 36 assisted reproduction laboratories monitoring environmental conditions and instrument parameters using the same quality-control application. Reproductive BioMedicine Online. 2019 Jul 1;39(1):63-74. DOI: https://doi.org/10.1016/j.rbmo.2019.03.204
Royal Decree No. M/76 dated 21/11/1424H. Royal Decree No. (A/90) dated 27/8/1412H, Royal Decree No. (A/13) dated 3/3/1414H, Royal Decree No. (A/91) dated 27/8/1412H, Shura Council Resolution No. (1/1) dated 3/3/1424H, and Council of Ministers' Resolution No. (260) dated 23/9/1424H. Amendment of the Implementing Regulations of the Law of Fertilization, Utero-Fetal and Infertility Treatment Units. Ministry of Health - the Kingdom of Saudi Arabia. 2004
Al-Hashemi N. Proposal for a law regarding the licensing of in vitro fertilization centers in the Lebanese Republic [Internet]. Beirut: Royal Academy of Science International Trust; 2011.
Leslie, Weikert., Christa, Fralick., Klaus, E., Wiemer. Essential Instruments and Disposable Supplies for an IVF Laboratory. In Vitro Fertilization: A Textbook of Current and Emerging Methods and Devices. 2019:79-84 DOI: https://doi.org/10.1007/978-3-319-43011-9_9
Leslie, Weikert., Christa, Fralick., Klaus, E., Wiemer. Essential Instruments and Disposable Supplies for an IVF Laboratory. 2012: p 55-59. DOI: https://doi.org/10.1007/978-1-4419-1780-5_8
Peak D, Khaldi R, Dubey AK. Procedures and Protocols in In Fertilization Laboratory. A Textbook of INFERTILITY Diagnosis, Management and IVF. 2012 May 18:283. DOI: https://doi.org/10.5005/jp/books/11639_20
Swain JE. A Comparison of Embryo Culture Incubators for the IVF Laboratory. Textbook of Assisted Reproduction. 2020:693-706.
WRIGHT BM. A simple control system for CO2 in incubators. J Clin Pathol. 1964 Jan;17(1):100-2. DOI: https://doi.org/10.1136/jcp.17.1.100
Swain JE. A Comparison of Embryo Culture Incubators for the IVF Laboratory. Textbook of Assisted Reproduction. 2020:693-706. DOI: https://doi.org/10.1007/978-981-15-2377-9_77
Gelo N, Kirinec G, Baldani DP, Vrčić H, Ježek D, Milošević M, Stanić P. Influence of human embryo cultivation in a classic CO2 incubator with 20% oxygen versus benchtop incubator with 5% oxygen on live births: The randomized prospective trial. Zygote. 2019 Jun;27(3):131-6. DOI: https://doi.org/10.1017/S0967199418000618
Bose S, Ghosh S, Dhang S, Dey P, Acharyya A. Design and Realization of an IoT-Based System for Real-Time Monitoring of Embryo Culture Conditions in IVF CO2 Incubators. InDoctoral Symposium on Intelligence Enabled Research 2022 Dec 22 (pp. 161-172). Singapore: Springer Nature Singapore. DOI: https://doi.org/10.1007/978-981-99-1472-2_14
Rodriguez-Wallberg KA, Waterstone M, Anastácio A. Ice age: Cryopreservation in assisted reproduction–An update. Reproductive biology. 2019;19(2):119-26. DOI: https://doi.org/10.1016/j.repbio.2019.04.002
Levi-Setti PE, Patrizio P, Scaravelli G. Evolution of human oocyte cryopreservation: slow freezing versus vitrification. Current Opinion in Endocrinology, Diabetes and Obesity. 2016;23(6):445-50.
Pegg DE. Principles of cryopreservation. Cryopreservation and freeze-drying protocols. 2015:3-19. DOI: https://doi.org/10.1007/978-1-4939-2193-5_1
Hubel A, Skubitz AP. Principles of cryopreservation. Biobanking of Human Biospecimens: Principles and Practice. 2017:1-21. DOI: https://doi.org/10.1007/978-3-319-55120-3_1
Ghumman S. “Freeze all” protocol–Has the debate concluded?. Fertility Science and Research. 2015;2(2):90-4. DOI: https://doi.org/10.4103/2394-4285.196783
Gosden RG. General principles of cryopreservation. Human fertility: Methods and protocols. 2014:261-8. DOI: https://doi.org/10.1007/978-1-4939-0659-8_11
Levi-Setti PE, Patrizio P, Scaravelli G. Evolution of human oocyte cryopreservation: slow freezing versus vitrification. Current Opinion in Endocrinology, Diabetes and Obesity. 2016 Dec 1;23(6):445-50. DOI: https://doi.org/10.1097/MED.0000000000000289
Rienzi LF, Iussig B, Dovere L, Fabozzi G, Cimadomo D, Ubaldi FM. Perspectives in gamete and embryo cryopreservation. InSeminars in Reproductive Medicine 2018 Sep (Vol. 36, No. 05, pp. 253-264). Thieme Medical Publishers. DOI: https://doi.org/10.1055/s-0038-1677463
Zegers-Hochschild F, Adamson GD, De Mouzon J, Ishihara O, Mansour R, Nygren K, Sullivan E, Van der Poel S. The international committee for monitoring assisted reproductive technology (ICMART) and the world health organization (WHO) revised glossary on ART terminology, 2009. Human reproduction. 2009;24(11):2683-7. DOI: https://doi.org/10.1093/humrep/dep343
Halvaei I, Ghazali S, Nottola SA, Khalili MA. Cleavage-stage embryo micromanipulation in the clinical setting. Systems biology in reproductive medicine. 2018;64(3):157-68. DOI: https://doi.org/10.1080/19396368.2017.1422197
Malter HE. Micromanipulation in assisted reproductive technology. Reproductive BioMedicine Online. 2016;32(4):339-47. DOI: https://doi.org/10.1016/j.rbmo.2016.01.012
Varghese AC, Sjoblom P, Jayaprakasan K. A Practical Guide to Setting Up an IVF Lab, Embryo Culture Systems and Running the Unit. JP Medical Ltd; 2013 Jul 30.
Jones C, Kashir J, Seres B, Chan J, Ewald K, Coward K. Fundamental laboratory skills for clinical embryologists. Textbook of Clinical Embryology. 2013:219.
JEITA. VOC emission rate specification for personal computers and tablet devices (ver 1) Japan Electronics and Information Technologies Industries Association, Tokyo. 2014.
Funaki R, Tanabe SI, Tanaka H, Nakagawa T. Measurements of chemical emission rates from portable PC and electronic appliances. Journal of Asian architecture and building engineering. 2003;2(2):55-9. DOI: https://doi.org/10.3130/jaabe.2.b55
Mortimer D, Cohen J, Mortimer ST, Fawzy M, McCulloh DH, Morbeck DE, Pollet-Villard X, Mansour RT, Brison DR, Doshi A, Harper JC. Cairo consensus on the IVF laboratory environment and air quality: report of an expert meeting. Reproductive BioMedicine Online. 2018 Jun 1;36(6):658-74. DOI: https://doi.org/10.1016/j.rbmo.2018.02.005
Bolton VN. Laboratory Procedures for Assisted Reproduction. In: Bhattacharya S, Hamilton M, editors. Reproductive Medicine for the MRCOG. Cambridge: Cambridge University Press; 2021. p. 93–112. DOI: https://doi.org/10.1017/9781108861724.009
Cohen J, Alikani M, Gilligan A, Schimmel T. Setting up an ART laboratory. InTextbook of assisted reproductive techniques. 2012. (pp. 41-48). CRC Press. DOI: https://doi.org/10.3109/9781841849713-5
Buxbaum E. Biophysical chemistry of proteins: an introduction to laboratory methods. Springer Science & Business Media; 2010 Nov 18.
Downloads
Published
Issue
Section
License
Copyright (c) 2023 Mabrouka Rahoma, Sara A Hwisa, Mabrouka Alfazzani Jira, Jira3 Mofeda M. Faraj, Enas Abdulsalm Ramih , Sokina Abobaker Almesawey, Fathia Ali Sadik Godid7 (Author)
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.