Study on Ginger as a Treatment for Stress and Anxiety Comparing With Diazepam

Authors

  • Ashraf Fatah Alzalitini Department of Pharmacology Dentist Faculty Tripoli University- Tripoli- Libya Author
  • Naima M. El-Kakalli Department of oral pathology - Dentist Faculty Tripoli University- Tripoli- Libya. Author
  • Wafa Mokhtar Issadiq Department of oral pathology- Dentist Faculty Gharyan University- Gharyan- Libya Author

DOI:

https://doi.org/10.54361/;JMR.20.2.83

Keywords:

Ginger, Behavior, Stress, Anxiety, Diazepam

Abstract

Background: The psychological anxiety is considered one of the most significant animals of the modern era. The most common causes natural indictors that lead to tension, severe stress and un-desirable mental problems or disease are stress Anxiety problems or disease that considered as most frequently appearing as disorders. Anxiety disease is diagnosing as condition that showed or indicate to serious and severe or pathological case as the essential disturbance emotional tone. Aim: In this study, ginger was tested in both diluted and concentrated forms suspension to evaluate its potential to alleviate psychological anxiety. it was compared against a positive control (diazepam) and negative control (water). To determine the anti-anxiety action of plant Ginger syrup extract. Diazepam is golden standard act as blocking or antagonized of stress and anxiety.Methodology: Experimental study was conducted in 2026. using animals albino mice and elevated plus-maze model (EPM) as a good standard technique for determined anti-anxiety behavior and stress inhibited. It is a validated and reliable measure of psychological anxiety, an animal's movement and crossing in an open area of elevated plus-maze indicates the absence of psychological anxiety, whereas its movement in an enclosed area indicates the presence of psychological anxiety.Results: This study, which relied on the use of ginger extract to reduce symptoms of anxiety like behavior and stress, because when treated animals with ginger lead to increased time spent and number of crossing and number of entries to open arms of elevated plus-maze instrument. clearly indicate or showed me that this extract is good and beneficial in stress management and reducing anxiety, especially after comparing it to golden standard Diazepam, the leading drug in this field. This clear results to important natural products as ginger extraction replace chemical substances.Conclusion: This  experimental study using male  albino mice as animals,  was it is been done to appear  possibility effects of plant Ginger extraction to inhibit stress and  anxiety behavior by using elevated plus-maze technique. This experimental study, was indicate or observed clear antagonized or blocking action to stress and anxiety induced-like behavior by used plant ginger extract or suspension in safe compatible suitable concentration. These good results to important ginger natural substances replace chemical compounds.

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Published

30-08-2026

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How to Cite

1.
Alzalitini A, El-Kakalli N, Issadiq W. Study on Ginger as a Treatment for Stress and Anxiety Comparing With Diazepam. LJMR [Internet]. 2026 Aug. 30 [cited 2026 Sep. 2];20(2):580-9. Available from: https://ljmr.ly/index.php/ljmr/article/view/630

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