Knowledge, Awareness, and Medication Adherence to Clopidogrel Therapy Among Patients in Zawiya, Libya: A Cross-Sectional Study

Authors

  • Zahra Abdulhamid Balkhayr Department of surgery, faculty of medicine, University of Zawiya Author
  • Hanan Alhadi Thwer Faculty of Medical Technology, University of Zawiya Author
  • Wayel A. Almrabet Faculty of Medical Technology, University of Zawiya Author
  • Badareddin A. Abousnena Department of Radiology, Faculty of Medical Technology, University of Zawiya Author
  • Hanan Arragebe Department of Radiology, Faculty of Medical Technology, University of Zawiya Author
  • Nasrien Ali Elfarrah Libyan Medical Research Center Author

DOI:

https://doi.org/10.54361/LJMR.20.2.73

Keywords:

Clopidogrel, medication adherence, patient awareness, bleeding risk, drug interactions, cross-sectional study, Libya

Abstract

Background: Clopidogrel is a widely used antiplatelet agent; however, its safe and effective use depends on patients’ knowledge, awareness, and adherence. Objective: This study aimed to assess patients’ knowledge, awareness, and adherence to clopidogrel therapy in Zawiya City, Libya, and to identify associated sociodemographic and clinical factors. Methods: A descriptive cross-sectional study was conducted among 150 clopidogrel users using a structured questionnaire covering knowledge, safety awareness, and medication practices. Data were analyzed using descriptive statistics and Chi-square tests. Results: Most participants were aware that clopidogrel prevents thrombotic events (70.0%) and increases bleeding risk (68.0%). However, important gaps were identified in awareness of drug interactions and peri-procedural precautions. Educational level was significantly associated with awareness of bleeding risk (p = 0.002) and current medication use (p = 0.032). Chronic disease status was significantly associated with awareness of analgesic interactions (p = 0.018) and consultation before analgesic use (p = 0.030). Age was significantly associated with consultation behaviour prior to painkiller use (p = 0.013).Conclusion: Although overall adherence was moderate, substantial deficiencies exist in patients’ safety-related knowledge. Targeted and structured educational interventions are needed to improve the safe use of clopidogrel.

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Published

09-08-2026

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How to Cite

1.
Balkhayr Z, Thwer H, Almrabet W, Abousnena B, Arragebe H, Elfarrah N. Knowledge, Awareness, and Medication Adherence to Clopidogrel Therapy Among Patients in Zawiya, Libya: A Cross-Sectional Study. LJMR [Internet]. 2026 Aug. 9 [cited 2026 Aug. 10];20(2):509-15. Available from: https://ljmr.ly/index.php/ljmr/article/view/610