Acute Myocardial Infarction as a Sequel of Cocaine Abuse

Authors

  • Aaedah A. A. Senussi Department of Medicine, Faculty of Medicine, Sebha University, Sebha, Libya Author

DOI:

https://doi.org/10.54361/ljmr.16205

Keywords:

Acute coronary syndrome, Cocaine abuser, Coronary spasm, Platelet aggregation, plaques

Abstract

Cocaine is considered the second most frequently used illicit drug and the most frequent cause of drug-related deaths in the world. Worldwide, the majority of cocaine users are younger people between the ages of 16 and 26 years old; and 11% of the general population is thought to have used it at some point in time. Cocaine users primarily administer cocaine orally, intranasally, intravenously, or by smoking it. Cocaine abuse leads to serious complications that involve all body systems, especially the cardiovascular system. In this study, we reported a case of acute myocardial infarction in a young patient without known chronic diseases. Twenty years old male patient presented with acute epigastric pain and repeated vomiting. He has a two-year history of cocaine abuse. All routine investigations were rapidly done; however, the patient collapsed and cardiopulmonary resuscitation (CPR) was performed. Clinical outcome: the patient, unfortunately, died after all trials to save his life and was diagnosed with severe myocardial infarction.

References

Rezkalla SH, Hale S, Kloner RA. Cocaine-induced heart diseases. Am Heart, 1990; vol.120: pp.1403–1408. DOI: https://doi.org/10.1016/0002-8703(90)90255-V

Satran A, Bart BA, Henry CR, Murad MB, Talukdar S, Satran D, Henry TD. Increased prevalence of coronary artery aneurysms among cocaine users. Circulation 2005 DOI: https://doi.org/10.1016/j.accreview.2005.09.001

Pletcher MJ, Kiefe CI, Sidney S, Carr JJ, Lewis CE, Hulley SB. Cocaine and coronary calcification in young adults: the Coronary Artery Risk Development in Young Adults (CARDIA) Study. AmHeart, 2005;vol.150: pp.921–926. DOI: https://doi.org/10.1016/j.ahj.2005.04.016

Kolodgie FD, Virmani R, Cornhill JF, Herderick EE, Smialek J. Increase in atherosclerosis and adventitial mast cells in cocaine abusers: an alternative mechanism of cocaine-associated coronary vasospasm and thrombosis. JAm Coll Cardiol 1991; vol.17:pp.1553–1560. DOI: https://doi.org/10.1016/0735-1097(91)90646-Q

Patrizi R, Passer V, Sciahbasi A, Summaria F, Rosano GM, Lioy E. (2006). Evidence of cocaine related coronary atherosclerosis in young patients with myocardial infarction. J Am Coll Cardiol , vol. 47, pp212. DOI: https://doi.org/10.1016/j.jacc.2005.12.060

Aaron E. Bair, MD, MSc, FAAEM, FACEP reviewing McCord J. (2013). Management of Cocaine-Associated Chest Pain and MI Circulation.

Lange RA, Hillis LD. (2016). Cardiovascular complications of cocaine use. N EnglJ.

Downloads

Published

31-12-2022

Issue

Section

Articles

How to Cite

1.
Senussi AAA. Acute Myocardial Infarction as a Sequel of Cocaine Abuse. LJMR [Internet]. 2022 Dec. 31 [cited 2024 Sep. 19];16(2):41-5. Available from: https://ljmr.ly/index.php/ljmr/article/view/48