Evaluation of Anemia Management in Hemodialysis Patients at Nephrology Diagnostic and Treatment Hospital

Zeineb Alsharef; Ahmed Abired; Taha Elsheredi

doi:10.26719//-05.18.2.08

Authors

Zeineb Alsharef Department of Basic nursing, Faculty of Nursing, University of Tripoli, Tripoli, Libya. Author
Ahmed Abired Department of Physiotherapy, Medical Science and Technologies Collage, Tripoli, Libya Author
Taha Elsheredi Department of Pharmacognasy, Faculty of pharmacy, Tripoli, Libya. Author

DOI:

https://doi.org/10.26719//-05.18.2.08

Keywords:

Pharmacies, Pharmacists, Patient Safety, Dispensing, Libya

Abstract

Purpose: This research aimed to evaluate how anemia is handled in hemodialysis patients and identify risk factors. Methods: This study involved analyzing the current approach to managing anemia in a nephrology hospital, comparing it to KDOQI guidelines. It was conducted in a hospital specializing in the diagnosis and treatment of kidney diseases. In Tripoli, Libya, documents were randomly selected between October 2023 and May 2024. There were 89 patients receiving hemodialysis in total. Analysis of data was performed using SPSS Version 26. Results: Data on age distribution revealed that the largest age group consisted of individuals aged 56-65 years, comprising 39 patients (43.8%), closely trailed by the age range of 36-55 years, with 37 patients (41.6%). The average age was 53.56 years and there was a male to female ratio of 1.7:1. The results of the study showed that most patients (59.6%) had a mean Hgb value below 10, while 21.3% had a mean Hgb value between 10 and 10.9. Additionally, only ≥11 cases reported a percentage of 19.1% and also stated that the average Hgb value was 9.716. Conclusions: This study reveals that anemia isunsatisfactorily controlled in hemodialysis patients. ESA hyporesponsivness played a critical role in lowering hemoglobin levels in the current therapeuticstrategies used.

References

WORLD HEALTH RANKINGS. Libya: Kidney Disease. 2020; Available from: https://www.worldlifeexpectancy.com/libya-kidney-disease.

Murtagh, F.E., J. Addington-Hall, and I.J. Higginson, The prevalence of symptoms in end-stage renal disease: a systematic review. Advances in chronic kidney disease, 2007. 14(1): p. 82-99.

Jiang, J., et al., The impact of short daily hemodialysis on anemia and the quality of life in Chinese patients. Brazilian Journal of Medical and Biological Research, 2013. 46(7): p. 629-633.

Suzuki, M., et al., Effects of anemia correction by erythropoiesis-stimulating agents on cardiovascular function in non-dialysis patients with chronic kidney disease. International heart journal, 2012. 53(4): p. 238-243.

Pınarbaşı, A.S., et al., Erythropoietin resistance index and the affecting factors in children with peritoneal dialysis. Blood Purification, 2021. 50(6): p. 942-951.

Mikhail, A., et al., Renal association clinical practice guideline on Anaemia of Chronic Kidney Disease. BMC nephrology, 2017. 18: p. 1-29.

Martinez-Vea, A., et al., Role of oxidative stress in cardiovascular effects of anemia treatment with erythropoietin in predialysis patients with chronic kidney disease. Clinical nephrology, 2012. 77(3): p. 171-181.

Go, A.S., et al., Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization. New England Journal of Medicine, 2004. 351(13): p. 1296-1305.

Silverberg, D.S., et al., The effect of correction of anaemia in diabetics and non‐diabetics with severe resistant congestive heart failure and chronic renal failure by subcutaneous erythropoietin and intravenous iron. Nephrology Dialysis Transplantation, 2003. 18(1): p. 141-146.

Al-Jabi, S.W., et al., A multicenter descriptive analysis of anemia management in hemodialysis patients and its association with quality of life. BMC nephrology, 2023. 24(1): p. 197.

Al-Ageel, N.A., et al., Appropriateness of anemia management in hemodialysis patients. Saudi Pharmaceutical Journal, 2012. 20(1): p. 85-91.

Akel, M., et al., Evaluation of the management of anemia in hemodialysis patients in Lebanon. Journal of Nephropharmacology, 2017. 6(2): p. 68-73.

Lizardi Gómez, L., et al., Factors related to the presence of anemia in patients with chronic kidney disease in hemodialysis. Annals of Hematology and Oncology, 2021. 8(1): p. 1326.