A Retrospective Study on Unveiling Demographic Trends and Clinical Significance for COVID-19 Patients in Tobruk City Hospital.
DOI:
https://doi.org/10.54361/LJM18.10Keywords:
COVID-19, Pandmic, respiratory infection, COVID-19 clinical traitsAbstract
This study investigates the impact of COVID-19 within the Tobruk Medical Center community, focusing on prevalence, clinical traits, and mortality rates. A comprehensive analysis was conducted on a cohort of 435 COVID-19 positive hospitalized patients from 2020 to 2022.Result Our findings reveal a higher incidence of COVID-19 among men, particularly in the 60-80 age group. Notable comorbidities, including diabetes and hypertension, underscore the vulnerability of individuals with underlying health conditions. Mortality rates, slightly higher at Tobruk Medical Center, show overlapping confidence intervals, emphasizing the need for cautious interpretation.Conclusion
The study provides crucial insights into demographic patterns and comorbidities affecting COVID-19 outcomes. The identification of risk factors, particularly the significant role of diabetes, contributes to our understanding of underlying health conditions in managing cases. Despite a slightly higher mortality rate at the medical center, the non-significant difference highlights the importance of considering potential limitations. This research contributes valuable information for guiding public health decisions and future pandemic responses, emphasizing the need for targeted interventions for at-risk populations.In conclusion, our study offers a nuanced understanding of the impact of COVID-19, providing essential knowledge to healthcare practitioners, policymakers, and researchers addressing the ongoing challenges posed by the pandemic.
References
Shang J, Wang Q, Zhang H, et al. The relationship between diabetes mellitus and COVID-19 prognosis: A Retrospective Cohort Study in Wuhan, China. American Journal of Medicine. 2021;134(1). doi:10.1016/j.amjmed.2020.05.033 DOI: https://doi.org/10.1016/j.amjmed.2020.05.033
Huang C, Wang Y, Li X, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. The Lancet. 2020;395(10223):497-506. doi:https://doi.org/10.1016/S0140-6736(20)30183-5 DOI: https://doi.org/10.1016/S0140-6736(20)30183-5
Guan W jie, Ni Z yi, Hu Y, et al. Clinical characteristics of coronavirus disease 2019 in China. New England Journal of Medicine. 2020;382(18):1708-1720. doi:10.1056/NEJMoa2002032 DOI: https://doi.org/10.1056/NEJMoa2002032
Goudouris ES. Laboratory diagnosis of COVID-19. J Pediatr (Rio J). 2021;97(1). doi:10.1016/j.jped.2020.08.001 DOI: https://doi.org/10.1016/j.jped.2020.08.001
Marhl M, Grubelnik V, Magdič M, Markovič R. Diabetes and metabolic syndrome as risk factors for COVID-19. Diabetes and Metabolic Syndrome: Clinical Research and Reviews. 2020;14(4). doi:10.1016/j.dsx.2020.05.013 DOI: https://doi.org/10.1016/j.dsx.2020.05.013
Costa FF, Rosário WR, Ribeiro Farias AC, de Souza RG, Duarte Gondim RS, Barroso WA. Metabolic syndrome and COVID-19: An update on the associated comorbidities and proposed therapies. Diabetes and Metabolic Syndrome: Clinical Research and Reviews. 2020;14(5). doi:10.1016/j.dsx.2020.06.016 DOI: https://doi.org/10.1016/j.dsx.2020.06.016
Muniyappa R, Gubbi S. COVID-19 pandemic, coronaviruses, and diabetes mellitus. Am J Physiol Endocrinol Metab. 2020;318(5). doi:10.1152/ajpendo.00124.2020 DOI: https://doi.org/10.1152/ajpendo.00124.2020
Chen Y, Yang D, Cheng B, et al. Clinical Characteristics and Outcomes of Patients with Diabetes and COVID-19 in Association with Glucose-Lowering Medication. Diabetes Care. 2020;43(7). doi:10.2337/dc20-0660 DOI: https://doi.org/10.2337/dc20-0660
Rodilla E, Saura A, Jiménez I, et al. Association of hypertension with all-cause mortality among hospitalized patients with COVID-19. J Clin Med. 2020;9(10). doi:10.3390/jcm9103136 DOI: https://doi.org/10.3390/jcm9103136
Savoia C, Volpe M, Kreutz R. Hypertension, a moving target in COVID-19. Circ Res. 2021;128(7). doi:10.1161/circresaha.121.318054 DOI: https://doi.org/10.1161/CIRCRESAHA.121.318054
Lau ES, McNeill JN, Paniagua SM, et al. Sex differences in inflammatory markers in patients hospitalized with COVID-19 infection: Insights from the MGH COVID-19 patient registry. PLoS One. 2021;16(4):e0250774-. https://doi.org/10.1371/journal.pone.0250774 DOI: https://doi.org/10.1371/journal.pone.0250774
Kragholm K, Andersen MP, Gerds TA, et al. Association between male sex and outcomes of coronavirus disease 2019 (COVID-19)—A Danish Nationwide, Register-based Study. Clinical Infectious Diseases. 2021;73(11):e4025-e4030. doi:10.1093/cid/ciaa924 DOI: https://doi.org/10.1093/cid/ciaa924
Doerre A, Doblhammer G. The influence of gender on COVID-19 infections and mortality in Germany: Insights from age- and gender-specific modeling of contact rates, infections, and deaths in the early phase of the pandemic. PLoS One. 2022;17(5 May). doi:10.1371/journal.pone.0268119 DOI: https://doi.org/10.1371/journal.pone.0268119
Kim L, Garg S, O’Halloran A, et al. Risk factors for intensive care unit admission and in-hospital mortality among hospitalized adults identified through the US Coronavirus Disease 2019 (COVID-19)-Associated Hospitalization Surveillance Network (COVID-NET). Clinical Infectious Diseases. 2021;72(9):e206-e214. doi:10.1093/cid/ciaa1012 DOI: https://doi.org/10.1093/cid/ciaa1012
Marand AJB, Bach C, Janssen D, et al. Lower urinary tract signs and symptoms in patients with COVID-19. BMC Infect Dis. 2021;21(1). doi:10.1186/s12879-021-06394-z DOI: https://doi.org/10.1186/s12879-021-06394-z
Tristão LS, Bresler R, Modesto VA, de Carvalho Fernandes R, Bernardo WM. Urological complications of COVID-19: a systematic review. International Braz J Urol. 2023;49(1). doi:10.1590/S1677-5538.IBJU.2022.0281 DOI: https://doi.org/10.1590/s1677-5538.ibju.2022.0281
Yanez ND, Weiss NS, Romand JA, Treggiari MM. COVID-19 mortality risk for older men and women. BMC Public Health. 2020;20(1). doi:10.1186/s12889-020-09826-8 DOI: https://doi.org/10.1186/s12889-020-09826-8
Rodriguez-Diaz CE, Guilamo-Ramos V, Mena L, et al. Risk for COVID-19 infection and death among Latinos in the United States: examining heterogeneity in transmission dynamics. Ann Epidemiol. 2020;52. doi:10.1016/j.annepidem.2020.07.007 DOI: https://doi.org/10.1016/j.annepidem.2020.07.007
Yanai H. Metabolic Syndrome and COVID-19. Cardiol Res. 2020;11(6). doi:10.14740/cr1181 DOI: https://doi.org/10.14740/cr1181
Tandogdu Z, Cai T, Koves B, Wagenlehner F, Bjerklund-Johansen TE. Urinary Tract Infections in Immunocompromised Patients with Diabetes, Chronic Kidney Disease, and Kidney Transplant. Eur Urol Focus. 2016;2(4). doi:10.1016/j.euf.2016.08.006 DOI: https://doi.org/10.1016/j.euf.2016.08.006
Mallick U. Hypertension in CoViD19. In: Cardiovascular complications of COVID-19. ; 2022. doi:10.1007/978-3-030-90065-6_13 DOI: https://doi.org/10.1007/978-3-030-90065-6_13
Drager LF, Pio-Abreu A, Lopes RD, Bortolotto LA. Is Hypertension a real risk factor for poor prognosis in the COVID-19 Pandemic? Curr Hypertens Rep. 2020;22(6). doi:10.1007/s11906-020-01057-x DOI: https://doi.org/10.1007/s11906-020-01057-x
Peng M, He J, Xue Y, Yang X, Liu S, Gong Z. Role of hypertension on the severity of COVID-19: A Review. J Cardiovasc Pharmacol. 2021;78(5). doi:10.1097/FJC.0000000000001116 DOI: https://doi.org/10.1097/FJC.0000000000001116
Kwon CY, Lee B, Chung SY, Kim JW, Kim SH. Oriental herbal medicine for insomnia in the elderly with hypertension A systematic review protocol. Medicine (United States). 2018;97(36). doi:10.1097/MD.0000000000012200 DOI: https://doi.org/10.1097/MD.0000000000012200
Ren J, Pang W, Luo Y, et al. Impact of Allergic Rhinitis and Asthma on COVID-19 Infection, Hospitalization, and Mortality. Journal of Allergy and Clinical Immunology: In Practice. 2022;10(1). doi:10.1016/j.jaip.2021.10.049 DOI: https://doi.org/10.1016/j.jaip.2021.10.049
Published
Issue
Section
License
Copyright (c) 2024 Ghareeb emraj ghareeb , Mabroka Fathy, Ahmed saeid safaiddin, Mhuanad Jummah, Manal Abdelfattah Muhammed (Author)
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.