Histopathological Grades of Colorectal Cancer: A One-Year Single-Center Study
DOI:
https://doi.org/10.54361/LJMR.19.2.08Keywords:
histopathology grade, age, colorectal cancer, LibyaAbstract
Background: Colorectal cancer (CRC) poses a major global health burden. It necessitates careful assessment for prognosis and treatment planning. Histopathological grading plays a key role in prognosis and treatment planning. Local studies are essential to understand CRC characteristics in specific populations and guide national health strategies. This study aimed to assess the histopathological grading patterns among individuals diagnosed with CRC during a one-year interval at the National Cancer Institute in Subrata, Libya, in 2024. Material and Methods: A cross-sectional retrospective analytic study was conducted involving 202 patients consecutively selected from the medical records of Subrata National Cancer Institute in 2024 using descriptive statistics and the chi-square test for association through SPSS software. Results: This study reveals that the majority of patients (78.7%) had Grade II tumors, with the highest frequency (35.1%) in patients over 60 years of age. Grade I and Grade III accounted for 17.8% and 3.5% of cases, respectively. A statistically significant association was found between histopathological grade and age (χ² = 14.9, p = 0.021) Conclusion: These findings underscore the urgent need for implementing targeted regional strategies, including enhanced public awareness campaigns, robust screening programs for early detection, and strengthening of the diagnostic infrastructure to improve CRC outcomes in Libya.
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Copyright (c) 2025 Sumaya Taher Draa , Fadia T.M Oshkondale, Adel M Abdallaa, Mohamed Khalifa Al-Kawash4, Mohamed Mohamed Altoumi, Kholoud Abd Al-Razzaq Kardmain, Khitam Mohamed Al-Shein (Author)
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