Sarcomatoid urothelial carcinoma in a bladder diverticulum: first report of an unusual case.
DOI:
https://doi.org/10.54361/Keywords:
Urinary bladder, Sarcomatoid urothelial carcinomaAbstract
70-year-old Libyan man presented with abdominal distension and gross hematuria. Cystescopy showed diverticulum in urinary bladder with tumor arising from its lateral wall. The tumor was composed of conventional urothelial carcinoma with sarcomatoid features. The clinical presentation and management are being discussed.
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References
Wright JL, Black PC, Brown GA, et al. (2007) Differences in survival among patients with sarcomatoid carcinoma, carcinosarcoma and urothelial carcinoma of the bladder. J. Urol. 178, 6: 2302-6.
Eble JN, Sauter G, Epstein JI, Sesterhenn I (2004) Pathology and genetics of tumours of the urinary system and male genital organs. IARC Press: Lyon.
Zhai QJ, Black J, Ayala AG, Ro JY (2007) Histologic variants of infiltrating urothelial carcinoma. Arch Pathol Lab Med. 131: 1244-56.
Sung MT, Wang M, MacLennan GT, et al. (2007) Histogenesis of sarcomatoid urothelial carcinoma of the urinary bladder: evidence for a common clonal origin with divergent differentiation Journal of Pathology, vol. 211, no. 4, pp. 420–430,
Kodzo A, Venyo G & Titi S (2014) Sarcomatoid Variant of Urothelial Carcinoma (Carcinosarcoma, Spindle Cell Carcinoma): A Review of the Literature Urology 9 pages. Article ID 794563.
Kanno J, Sakamoto A, Washizuka M, Kawai T, Kasuga T (1985) Malignant mixed mesodermal tumor of bladder occurring after radiotherapy for cervical cancer: report of a case. J Urol. 133, 5:854-6.
Lopez-Beltran A, Pacelli A, Rothenberg HJ et al. (1998) Carcinosarcoma and sarcomatoid carcinoma of the bladder: clinicopathological study of 41 cases. J Urol. 159, 5:1497-503.
Armah HB, Parwani AV (2007) Sarcomatoid urothelial carcinoma with choriocarcinomatous features: first report of an unusual case. Urology 70, 4: 11-14.
Hejtmancik JH, Klatt WW (1960) Co-existing carcinoma and sarcoma of the bladder. J Urol. 84:320–321.
Holtz F, Fox JE, Abell MR (1972) Carcinosarcoma of the urinary bladder. Cancer 29: 294–304.
Armstrong A, Wang M, Eble J et al. (2009) TP53 mutational analysis supports monoclonal origin of biphasic sarcomatoid urothelial carcinoma (carcinosarcoma) of the urinary bladder. Modern Pathology 22: 113–118.
Kishore TA, Bhat S, Albert AS, Augustine J (2005) A sarcomatoid carcinoma in a bladder diverticulum: A rare case. Indian J Med Sci. 59,10: 535-555.
Black P. C, Brown GA., and. Dinney CN et al. (2009) “The impact of variant histology on the outcome of bladder cancer treated with curative intent,” Urologic Oncology 27, 1: 3– 7.
Bansal A, Kumar N, Suresh C. Sharma SC (2013) Sarcomatoid variant of urothelial carcinoma of the urinary bladder. Journal of Cancer Research and Therapeutics 9, 4: 571-573.
Wang J, Wang F, LaGrange C et al. (2010) Clinical features of sarcomatoid carcinoma ( carcinosarcoma) of the urinary bladder: Analysis of 221 cases. Hindawi Publishing Corporation Sarcoma 7 pages, Article ID 454792.
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Copyright (c) 2017 L. S. Elbarghati , L. M. Azzouz, W.M Alsarraj (Author)

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