From accident lip bite to Lesion: Traumatic Neuroma of the Lower Lip: A Rare Case Report
DOI:
https://doi.org/10.54361/LJMR.20.2.46Keywords:
Traumatic neuroma, Lower lip, Peripheral nerve injury, Reactive lesion, Oral soft tissue lesion, Schwann cells, Nerve proliferation, Histopathology, Minor salivary glandsAbstract
Background: Traumatic neuroma is an uncommon, reactive, non-neoplastic proliferation of nerve tissue that develops following nerve injury or transection. It typically presents as a small, nodular lesion in areas prone to trauma, such as the lower lip, tongue, or mental foramen region. Clinically, it may appear as a painless or occasionally tender swelling and is often associated with a history of local trauma or chronic trauma. Case presentation: A 25-year-old Sudanese male presented to the Oral and Maxillofacial Surgery clinic with a localised swelling in the lower lip for approximately one week. The patient reported a history of repeated lip biting prior to the onset of the lesion. The swelling was initially small and gradually increased in size. It was painless, with no associated bleeding or discharge. Radiographic examination revealed no abnormality. An excisional biopsy was performed under local anaesthesia, and the specimen was submitted for histopathological evaluation, which confirmed the diagnosis of traumatic neuroma. Conclusion: This case highlights the importance of considering traumatic neuroma in the differential diagnosis of oral soft tissue lesions, particularly in the presence of a history of trauma. Histopathological examination remains the gold standard for definitive diagnosis, and surgical excision is associated with an excellent prognosis.
Downloads
References
1. Yang H, Dong Y, Wang Z, et al. Traumatic neuromas of peripheral nerves: diagnosis, management and future perspectives. Front Neurol. 2022;13:1039529.
2. Ziccardi VB, Steinberg MJ. Pathophysiology and management of traumatic neuromas. Oral Maxillofac Surg Clin North Am. 2020;32(1):45-53.
3. Grinsell D, Keating CP. Peripheral nerve reconstruction after injury: a review of clinical and experimental therapies. Biomed Res Int. 2020;2020:6982562.
4. Poppler LH, Parikh RP, Bichanich MJ, et al. Surgical interventions for the treatment of painful neuroma: a comparative meta-analysis. Plast Reconstr Surg. 2018;141(2):331-343.
5. Kim SM, Seo MH, Lee JH, et al. Clinical characteristics of traumatic neuromas in the oral cavity. J Oral Pathol Med. 2019;48(3):210-215.
6. Neville BW, Damm DD, Allen CM, Chi AC. Oral and Maxillofacial Pathology. 4th ed. St. Louis (MO): Elsevier; 2016.
7. Sisti TC, Greene GW. Traumatic neuroma of the oral cavity. Report of thirty-one new cases and review of the literature. Oral Surg Oral Med Oral Pathol. 1981;51(4):394-402.
8. Watson J, González M, Romero A, Kerns J. Neuromas of the hand and upper extremity. J Hand Surg Am. 2021;46(2):150-159.
9. Gruber H, Glodny B, Kopf H, Bendix N, Galiano K, Peer S. Practical experience with sonographically guided perineural instillation of stump neuroma: predictors of effects, success, and outcome. AJR Am J Roentgenol. 2008;190(5):1263-1269.
10. Sivapathasundharam B. Shafer's Textbook of Oral Pathology. 7th ed. New Delhi: Elsevier; 2021.
Thomas D, C, Vedantham R, Annamalai N, Pitchumani P, K. Intraoral bilateral intraoral traumatic neuroma: case report of a diagnostic challenge. J Indian Prosthodont Soc. 2021;21(4):430-433.
11. Nelke K, Janecek M, Pasicka E, Zak K, Lukaszewski M, Nienartowicz J, Glogolewski G, Maga J, Kuropka P, et al. Rare localisation of traumatic neuroma of the hard palate: case report. Oral Maxillofac Surg Cases. 2024.
12. Dobrzyński M. Rare localisation of traumatic neuroma of the hard palate: case report. Oral Maxillofac Surg Cases. 2024.
Downloads
Published
Issue
Section
License
Copyright (c) 2026 Yousef S.Z. Salem, Amna El-Gehani, Huda Alamaa, Safa T. Hammad (Author)

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Open Access Policy
Libyan journal of medical Research (LJMR).is an open journal, therefore there are no fees required for downloading any publication from the journal website by authors, readers, and institution.
The journal applies the license of CC BY (a Creative Commons Attribution 4.0 International license). This license allows authors to keep ownership f the copyright of their papers. But this license permits any user to download , print out, extract, reuse, archive, and distribute the article, so long as appropriate credit is given to the authors and the source of the work.
The license ensures that the article will be available as widely as possible and that the article can be included in any scientific archive.
Editorial Policy
The publication of an article in a peer reviewed journal is an essential model for Libyan journal of medical Research (LJMR). It is necessary to agree upon standards of expected ethical behavior for all parties involved in the act of publishing: the author, the journal editorial, the peer reviewer and the publisher.
Any manuscript or substantial parts of it, submitted to the journal must not be under consideration by any other journal. In general, the manuscript should not have already been published in any journal or other citable form, although it may have been deposited on a preprint server. Authors are required to ensure that no material submitted as part of a manuscript infringes existing copyrights, or the rights of a third party.
Authorship Policy
The manuscript authorship should be limited to those who have made a significant contribution and intellectual input to the research submitted to the journal, including design, performance, interpretation of the reported study, and writing the manuscript. All those who have made significant contributions should be listed as co-authors.
Others who have participated in certain substantive aspects of the manuscript but without intellectual input should only be recognized in the acknowledgements section of the manuscript. Also, one of the authors should be selected as the corresponding author to communicate with the journal and approve the final version of the manuscript for publication in the LJMR.
Peer-review Policy
- All the manuscripts submitted to LJMR will be subjected to the double-blinded peer-review process;
- The manuscript will be reviewed by two suitable experts in the respective subject area.
- Reports of all the reviewers will be considered while deciding on acceptance/revision or rejection of a manuscript.
- Editor-In-Chief will make the final decision, based on the reviewer’s comments.
- Editor-In-Chief can ask one or more advisory board members for their suggestions upon a manuscript, before making the final decision.
- Associate editor and review editors provide administrative support to maintain the integrity of the peer-review process.
- In case, authors challenge the editor’s negative decision with suitable arguments, the manuscript can be sent to one more reviewer and the final decision will be made based upon his recommendations.












https://portal.issn.org/resource/ISSN/2413-6069