Perforating Dermatosis as a cause of chronic pruritus Diabetic Patient on Hemodialysis or vice versa
DOI:
https://doi.org/10.54361/LJMR.20.1.28Keywords:
Perforating dermatosis, diabetes mellitus, chronic kidney disease, dialysis, pruritusAbstract
Perforating Dermatosis (PD) is a rare cutaneous disorder associated with chronic kidney disease (CKD) and diabetes mellitus (DM), characterized by the transepidermal elimination of dermal components. Despite its prevalence among dialysis patients, it remains underreported, particularly in our region. We present a case of a 70-year-old male with long standing diabetes and CKD on hemodialysis for seven years, who developed widespread perforating skin lesions. This case highlights the clinical presentation, and management challenges, emphasizing the importance of recognizing (PD) in nephrology and dermatology practice.
Downloads
References
1. Rapini RP, Herbert AA, Drucker CR. Acquired perforating dermatosis. Evidence for combined transepidermal elimination of both collagen and elastin fibers. Arch Dermatol. 1989;125(8):1074-1078.
2. Saray Y, Seçkin D, Bilezikçi B. Acquired perforating dermatosis: Clinicopathological features in twenty-two cases. J Eur Acad Dermatol Venereol. 2006;20(6):679-688.
3. Morton CA, Lafferty M, Hau C, Henderson I, Jones M. Pruritus and skin hydration during dialysis. Nephrol Dial Transplant. 1996;11(10):2031-2036.
4. Masmoudi A, Sellami T, Mnif F, et al. Acquired perforating dermatosis in a diabetic hemodialysis patient: A case report. Nephrol Ther. 2010;6(5):324-327.
5. Saif GB, Elgarhy LH. Perforating dermatosis in diabetic patients: Clinical and histopathological study. Indian J Dermatol. 2013;58(5):345-349.
6. Saray Y, Seçkin D, Bilezikçi B. Acquired perforating dermatosis: Clinicopathological features in twenty-two cases. J Eur Acad Dermatol Venereol. 2006;20(6):679-688. DOI: 10.1111/j.1468-3083.2006.01594.
7. Morton CA, Henderson IS, Jones MC, Lowe JG. Acquired perforating dermatosis in a British dialysis population. Br J Dermatol. 1996;135(5):671-677. DOI: 10.1046/j.1365-2133.1996.d01-949.
8. Chan LS, Cooper KD, Hoang MP. The spectrum of acquired perforating dermatosis. Arch Dermatol. 1995;131(10):1216-1221. DOI: 10.1001/archderm.1995.01690220070012.
9. Hafeez F, Shafi F, Kazmi AH. Acquired perforating dermatosis: A report of three cases successfully treated with narrow-band ultraviolet B therapy. Photodermatol Photoimmunol Photomed. 2019;35(1):51-54.
Downloads
Published
Issue
Section
License
Copyright (c) 2026 Ail Alahrash , W. Ashaibani (Author)
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Open Access Policy
Libyan journal of medical Research (LJMR).is an open journal, therefore there are no fees required for downloading any publication from the journal website by authors, readers, and institution.
The journal applies the license of CC BY (a Creative Commons Attribution 4.0 International license). This license allows authors to keep ownership f the copyright of their papers. But this license permits any user to download , print out, extract, reuse, archive, and distribute the article, so long as appropriate credit is given to the authors and the source of the work.
The license ensures that the article will be available as widely as possible and that the article can be included in any scientific archive.
Editorial Policy
The publication of an article in a peer reviewed journal is an essential model for Libyan journal of medical Research (LJMR). It is necessary to agree upon standards of expected ethical behavior for all parties involved in the act of publishing: the author, the journal editorial, the peer reviewer and the publisher.
Any manuscript or substantial parts of it, submitted to the journal must not be under consideration by any other journal. In general, the manuscript should not have already been published in any journal or other citable form, although it may have been deposited on a preprint server. Authors are required to ensure that no material submitted as part of a manuscript infringes existing copyrights, or the rights of a third party.
Authorship Policy
The manuscript authorship should be limited to those who have made a significant contribution and intellectual input to the research submitted to the journal, including design, performance, interpretation of the reported study, and writing the manuscript. All those who have made significant contributions should be listed as co-authors.
Others who have participated in certain substantive aspects of the manuscript but without intellectual input should only be recognized in the acknowledgements section of the manuscript. Also, one of the authors should be selected as the corresponding author to communicate with the journal and approve the final version of the manuscript for publication in the LJMR.
Peer-review Policy
- All the manuscripts submitted to LJMR will be subjected to the double-blinded peer-review process;
- The manuscript will be reviewed by two suitable experts in the respective subject area.
- Reports of all the reviewers will be considered while deciding on acceptance/revision or rejection of a manuscript.
- Editor-In-Chief will make the final decision, based on the reviewer’s comments.
- Editor-In-Chief can ask one or more advisory board members for their suggestions upon a manuscript, before making the final decision.
- Associate editor and review editors provide administrative support to maintain the integrity of the peer-review process.
- In case, authors challenge the editor’s negative decision with suitable arguments, the manuscript can be sent to one more reviewer and the final decision will be made based upon his recommendations.
https://portal.issn.org/resource/ISSN/2413-6069
